Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but they are uncommon On this malignancy when compared with other lymphoid neoplasms. CHD2 is mutated in five% of CLL and seven% of MBL.75 The histone methyltransferase SETD2 and ARID1A can also be mutated in a small proportion of patients. Of Be aware, MYD